WEL Substance Profile
CAS: 50-00-0 | Notation: Carcinogen (IARC Group 1), skin sensitiser
Current WES
1
ppm
New WEL (Dec 2026)
0.3
ppm
Change
-70%
reduction
Formaldehyde is classified as a Group 1 carcinogen by IARC, with sufficient evidence of causing nasopharyngeal cancer and leukaemia in humans. It is also a strong respiratory and skin sensitiser that can cause occupational asthma and allergic contact dermatitis. At concentrations above 0.1 ppm, formaldehyde causes irritation of the eyes, nose, and throat — symptoms that serve as a warning of exposure but do not protect against carcinogenic effects at lower concentrations. Chronic exposure at levels below the current WES has been associated with chronic rhinitis, decreased lung function, and increased susceptibility to respiratory infections. Formaldehyde is highly water-soluble, which means it is rapidly absorbed in the upper respiratory tract where it exerts its primary carcinogenic effects on nasal and nasopharyngeal tissues.
Personal air sampling using DNPH-coated silica gel sorbent tubes with a calibrated pump at 0.1 to 1.5 L/min. Analysis by HPLC with UV detection following NIOSH Method 2016 or AS 2365.5. Direct-reading photoionisation detectors can supplement tube sampling for real-time exposure assessment but are not specific to formaldehyde and may overestimate in mixed vapour environments.
EHS Atlas tracks formaldehyde monitoring data, manages health surveillance for exposed workers, and documents ventilation system maintenance and testing records.
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