WEL Substance Profile
CAS: 7439-96-5 | Notation: Inhalable fraction
Current WES
1
mg/m³
New WEL (Dec 2026)
0.02
mg/m³
Change
-98%
reduction
Chronic manganese exposure causes manganism, a progressive neurological condition with symptoms resembling Parkinson's disease including tremors, difficulty walking, facial muscle rigidity, and cognitive impairment. Early symptoms include fatigue, headache, muscle cramps, and mood changes that are frequently misdiagnosed. Manganese accumulates in the brain's basal ganglia, and neurological damage is largely irreversible once established. Reproductive toxicity has also been demonstrated, with reduced fertility observed in exposed workers. Respiratory effects include chemical pneumonitis from acute inhalation of manganese fume and chronic inflammatory changes in the lungs from prolonged exposure to manganese dust.
Personal air sampling using a calibrated sampling pump with IOM inhalable sampler and mixed cellulose ester filter. Analysis by ICP-MS or ICP-OES after acid digestion. Sampling duration should cover a full shift to capture time-weighted average exposure. Static monitoring may supplement personal sampling to characterise spatial exposure patterns.
EHS Atlas tracks your manganese exposure data against the incoming WEL and identifies control gaps before 1 December 2026. Automated alerts when monitoring results approach the new limit.
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